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How cells handle broken chromosomes

(PhysOrg.com) -- After being recognized and initially processed by the cellular machinery, the broken chromosome is extensively scanned for homology and the break itself is later tethered to the...

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Elderly women with 'dowager's hump' may be at higher risk of earlier death

(PhysOrg.com) -- Hyperkyphosis, or "dowager's hump" -- the exaggerated forward curvature of the upper spine seen commonly in elderly women -- may predict earlier death in women whether or not they have...

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Genome-wide map shows precisely where microRNAs do their work

MicroRNAs are the newest kid on the genetic block. By regulating the unzipping of genetic information, these tiny molecules have set the scientific world alight with such wide-ranging applications as...

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Safer stem cells for therapy

(PhysOrg.com) -- When stem cell researchers in Japan and the United States announced in 2007 that they had developed long-sought methods to return fully developed adult human cells to an embryonic-like...

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New research to reduce drug side-effects

They are a group of drugs which millions of people rely on to keep pain at bay but they can have unwanted side-effects which are sometimes more serious than the original health problem. Now scientists...

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Stem cell research: From molecular physiology to therapeutic applications

Stem cell research promises remedies to many devastating diseases that are currently incurable, ranging from diabetes and Parkinson's disease to paralysis. Totipotent embryonic stem cells have great...

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Life and death in the living brain: Recruitment of new neurons slows when old...

(PhysOrg.com) -- Like clockwork, brain regions in many songbird species expand and shrink seasonally in response to hormones. Now, for the first time, University of Washington neurobiologists have...

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Researchers identify protein essential for cell division in blood-forming...

University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-forming stem cells. Loss of the protein...

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Technology tethers free radicals

The science world is abuzz with news of a new platform technology developed by physicists at the University of Sydney - technology that can be used in areas as diverse as disease detection through to...

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Reprogramming stem cells to a more basic form results in more effective...

Chinese stem cell scientists have published new research that improves the survival and effectiveness of transplanted stem cells. The research led by Dr Hsiao Chang Chan, from the Chinese University of...

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How can the salamander help fight degenerative disease?

Ever asked yourself why some animals can regenerate lost body parts, yet we can't grow back a limb? A new Australian research collaboration is offering a chance to solve this puzzle in the fight to...

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Study shows vast majority of cells close to death after toxin exposure can...

(Phys.org) -- The vast majority of cells that appear to be on a one-way track to death after exposure to toxins can bounce back completely after those toxins are removed, Johns Hopkins scientists...

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Researchers see surprising twist to protein misfolding

An effort to develop software that unravels the complexities of how proteins fold is paying dividends in new findings on how they misfold, according to researchers at Rice University.

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Research shows great promise for millet grains

Climate change, water scarcity, increasing world population, and rising food prices are only some of the socioeconomic factors that threaten agriculture and food security worldwide, especially for...

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Assembly of a protein degradation machine could lead to treatments in cancer,...

Kansas State University scientists helped discover new details about an intricate process in cells. Their finding may advance treatments for cancer and neurological diseases.

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A new gene-expression mechanism is a minor thing of major importance

A rare, small RNA turns a gene-splicing machine into a switch that controls the expression of hundreds of human genes. Howard Hughes Medical Institute Investigator and professor of Biochemistry Gideon...

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'Better detection' for Alzheimer's and cancers

A new chemical discovery will lead to better monitoring and treatment for cancers and degenerative diseases, according to latest research by scientists.

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Watching molecules 'dance' in real time

(Phys.org) —A new technique which traps light at the nanoscale to enable real-time monitoring of individual molecules bending and flexing may aid in our understanding of how changes within a cell can...

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Commensal bacteria were critical shapers of early human populations

Using mathematical modeling, researchers at New York and Vanderbilt universities have shown that commensal bacteria that cause problems later in life most likely played a key role in stabilizing early...

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Study: Brain energy crisis may spark Parkinson's

Parkinson's disease may stem from an energy crisis in the brain, years before symptoms appear.

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